Self-identified Race And Area Deprivation Index In Patients With Invasive Lobular Carcinoma of the breast: associations with tumor characteristics and event free survival
A recent analysis of the SEER database showed that racial/ethnic identity is associated with worse outcomes in those with ILC. We wanted to validate these findings in our institutional database of ILC patients and investigate whether including socioeconomic factors, measured using the Area Deprivation Index (ADI), would influence the associations between race and outcomes.
On univariate analysis, black race, high area deprivation, and overweight/obese category body mass index (BMI) were each shown to reduce event free survival (EFS). In a multivariate analysis, however, overweight/obese category BMI remained the only significant factor associated with reduced EFS.
Our findings illustrate complex associations between many factors that impact breast cancer outcomes. Chiefly, our data suggests that the relationship between race and EFS was mitigated by ADI and obesity, suggesting that race is not an independent predictor of outcomes for ILC patients.
