University of California San Francisco

UCSF Department of Surgery
April 23, 2023
Dr. Rita Mukhtar  and Postdoc Fellow, Kirithiga Ramalingam
UCSF Lobular Breast Cancer Research Program Principal Investigator Dr. Rita Mukhtar and Postdoc Fellow, Kirithiga Ramalingam at the 24th Annual American Society of Breast Surgeons Meeting.

Successful Breast Conservation After Neoadjuvant Chemotherapy in Lobular Breast Cancer: The Role of Menopausal Status in Response to Treatment

While neoadjuvant chemotherapy (NAC) has been shown to increase rates of breast conservation surgery (BCS) for breast cancer, response rates in invasive lobular carcinoma (ILC) appear lower than other histologic subtypes. Some data suggest higher response rates to NAC in premenopausal versus postmenopausal patients, but this has not been studied in ILC. We evaluated the rates of successful BCS after NAC in patients with ILC stratified by menopausal status.